Cart
sales@molnova.com
PAβN dihydrochloride
CAS No. 100929-99-5
PAβN dihydrochloride ( MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride )
Catalog No. M22016 CAS No. 100929-99-5
PAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
|
| 10MG | 64 | In Stock |
|
| 25MG | 97 | In Stock |
|
| 50MG | 138 | In Stock |
|
| 100MG | 206 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePAβN dihydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionPAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?
-
DescriptionPAβN dihydrochloride is an inhibitor of efflux pump. PAβN reduces the MICs in nine ciprofloxacin-resistant isolates, and in four of these, PAβN increases the susceptibility by twofold.?Moreover, PAβN restores ciprofloxacin susceptibility in five of the ciprofloxacin-resistant isolates.?In addition, clear effects of NMP on the ciprofloxacin MICs are seen for 20 of these ciprofloxacin-resistant isolates.
-
SynonymsMC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorBacterial; efflux pump
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number100929-99-5
-
Formula Weight519.47
-
Molecular FormulaC25H32Cl2N6O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:95mg/ml (182.88 Mm);H2O:14.29 mg/mL (27.51 mM; Need ultrasonic)
-
SMILESCl.Cl.N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1=CC2=CC=CC=C2C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lomovskaya O, et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.
molnova catalog
related products
-
JSF-4088
JSF-4088 (JSF4088) is a novel antitubercular agent with potent in vitro antitubercular potency (MIC=19 nM).
-
D13-9001
D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.
-
ANT431
ANT431 is a novel potent metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2.
